Biochemical Profile of Chronic Kidney Disease (CKD) Patients Across Various Age and Gender Groups Visiting a Tertiary Care Centre: A Retrospective Observational Study

Abstract

Background: Chronic Kidney Disease (CKD) represents a significant public health concern with distinct biochemical abnormalities that vary across demographic groups. Understanding the biochemical profile of CKD patients stratified by age and gender can offer insights into disease progression and management strategies.
Methods: This retrospective observational study analyzed the biochemical profiles of CKD patients visiting a tertiary care center over two years. The study included patients grouped by age (18–40, 41–60, >60 years) and gender. Parameters such as serum creatinine, urea, potassium, hemoglobin, and calcium levels were evaluated and compared.
Results: A total of 350 CKD patients were included, with males comprising 58% and females 42%. Serum creatinine levels were significantly elevated in males compared to females (p<0.05). Younger patients (18–40 years) exhibited lower hemoglobin levels, while elderly patients (>60 years) showed more pronounced hyperkalemia and hypocalcemia.
Conclusion: Biochemical profiles in CKD patients exhibit significant variations based on age and gender. Tailored management strategies are necessary to address these disparities and improve outcomes.