Impact of Intraoperative Blood Pressure Management on Postoperative Organ Function in High-Risk Surgery Patients

Abstract

Maintaining optimal intraoperative blood pressure (BP) is crucial for the preservation of organ function, particularly in high-risk surgical patients. This study investigates the effect of different intraoperative BP management strategies on postoperative organ function, specifically renal and hepatic outcomes, in patients undergoing major cardiovascular and abdominal surgeries. We conducted a prospective, observational study comparing tight BP control (mean arterial pressure between 70–85 mmHg) versus standard BP management in high-risk surgery patients. Postoperative organ function was assessed using serum creatinine, liver enzymes, and incidence of postoperative acute kidney injury (AKI) and liver dysfunction. Our results indicated that tight intraoperative BP control was associated with a significantly lower incidence of AKI, improved renal function, and fewer cases of hepatic dysfunction in the postoperative period. Patients in the tight control group also experienced a faster recovery in terms of organ function. These findings suggest that individualized intraoperative BP management may play a critical role in reducing postoperative organ dysfunction and improving recovery in high-risk surgical patients.