Impact of Perioperative Blood Glucose Management on Postoperative Infection Rates in Diabetic Patients Undergoing Major Surgery

Abstract

Perioperative hyperglycemia is associated with an increased risk of postoperative infections, particularly in diabetic patients undergoing major surgery. This study investigates the effects of tight blood glucose control during the perioperative period on the incidence of postoperative infections in diabetic patients. A total of 200 patients with diabetes undergoing elective major surgery were randomized into two groups: one group received intensive blood glucose management with insulin infusion to maintain glucose levels between 80-110 mg/dL, while the control group received standard care. Postoperative infection rates, including wound infections and sepsis, as well as recovery time and length of hospital stay, were recorded. The results demonstrated that patients in the intensive blood glucose control group had significantly lower infection rates and a shorter hospital stay compared to the control group. These findings support the implementation of tight perioperative glucose control as an effective strategy to reduce postoperative infections and improve recovery in diabetic patients undergoing major surgeries.